|Degree Code:||Degree Name:||MASTER OF SCIENCE IN ORGANIC CHEMISTRY|
|Degree Description:||Click to View|
|Admission Requirements||View Details|
(a) The common regulations for the Masters degrees in the School of Physical Sciences shall apply.
(b) In addition to meeting (a) above, candidates wishing to register for Master of Science in Organic Chemistry must have any of the following:
(i) A degree of the University of Nairobi of at least an Upper Second Class Honours in Chemistry or equivalent from any other institution recognized by the Senate.
(ii) A lower Second Class honours degree of the University of Nairobi in Chemistry or equivalent from any other institution recognized by the Senate plus at least two years relevant research/work experience
(iii) A pass degree of the University of Nairobi in Chemistry or equivalent from any other institution recognized by the Senate plus at least five years relevant research/work experience.
In the first year all students are required to take ten units. Eight of these are the Core Units and the remaining two chosen from the elective units. On successful completion of the first year, students devote the second year to research in a given area and writing up of an MSc Thesis.
|Duration and Mode of Study||View Details|
(i) The course shall be evaluated in terms of units; a course unit being defined as series of 45 one-hour lecture equivalents. For this purpose one 1-hour lecture is equivalent to one 2-hour tutorial or one 3-hour practical or any combination of these that may be recommended by the School Board and approved by Senate.
(ii) The course consists of coursework, continuous assessment, written examination and a research project.
(iii) The continuous assessment shall comprise tests, assignments, practical in certain units and term papers.
(iv) The candidate shall be required to take 10 course units; 9 of which shall be core and 1 elective.
(v) In second year the candidate shall undertake a mandatory research and thesis equivalent to eight course units.
(vi) The course shall be covered in a minimum of four (4) and maximum of eight (8) semesters of 15 weeks each.
Mode of study
Day programme: MONDAY- FRIDAY 8 AM -5 PM
Evening programme: This is tailored for those working during normal working hours. MONDAY- FRIDAY 5.30 PM - 8.30 PM; SATURDAY 8 AM - 5 PM
|Examinations Regulations||View Details|
1 A candidate shall not be allowed to sit any examination unless he or she has attended at least two thirds of the total lecture hours.
2 Each unit shall be examined by a two hour written examination at the end of the semester during which the course is offered.
3 The end of semester examination shall constitute 70% of the total marks in each course while the continuous assessment shall constitute 30%. Continuous assessment shall comprise of assignments, tests, term papers and practical where applicable.
4 Pass mark for each course unit shall be 50%
5 In order to proceed to the second year, a candidate must pass in all ten course units.
6 A candidate who fails in not more than two course units (score of 40—49 %) shall be allowed to take supplementary examinations in the failed units in accordance with The School of Physical Sciences’ Regulations and Senate's approval
7 A candidate who scores less than 40 % in a unit shall be discontinued
8 The maximum score for a supplementary examination shall be 50%.
9 A candidate who fails in more than three courses or does not pass in the supplementary examinations shall be discontinued from the programme.
1 The Second year of study shall be by thesis (equivalent to eight units) based on a research proposal submitted and approved by the end of first year. The thesis shall be examined in accordance with the common Regulations of the University of Nairobi for the Masters Degrees in all Schools and Faculties.
2 Each candidate will submit, with approval of supervisors, a duly completed thesis for examination. The candidate shall defend the research findings at a Board of Examiners meeting recommended by the School.
C. OTHER CHARGES:
D. All fees due should be paid before registration can be effected.
E. Appropriate field work fee shall be charged separately.
F. These are the minimum recommended research funds in each category.
Fees will be payable by Money Order or Bankers Cheques only drawn in favour of University of Nairobi Enterprises and Services (UNES) Limited.
The Fees indicated below do not include accommodation, personal maintenance costs, books and stationery.
A book allowance of about 40,000/= will be required.
|objectives of the course||View Details|
Organic chemistry is an important interface between theory and application in chemical sciences. Synthetic and natural products chemistry are the two key areas in organic chemistry.
This is a new program that the Department is introducing for the first time. Its introduction has been occasioned by the ever increasing demand for trained personnel in synthetic and natural products chemistry.
Graduate students will in addition to the traditional areas of chemistry take courses in organometallic chemistry, secondary metabolites, medicinal chemistry, research methods and advanced electroanalytical chemistry.
Graduates find employment in the following areas: government departments, parastatals, research and development institutes, chemical process design, production, quality control, pharmaceuticals, process industry, plastics industry, pulp and paper industry, tanning industry, consumer industry, textile industry, dyes industry, cosmetics industry, forensic science, paints industry, water analyst, biotechnology, food science industry, agriculture, organic fertilizer industry, food flavour industry, perfumery industry, oil and petroleum industry, paints industry just to name a few.
|Level : 1|
|Semester: Non Specified|
|Course Code||Course Name||Course Hours|
|SCH516||Special Topics In Organic Chemistry||45||View Description|
Special Topics In Organic Chemistry Description
Topics of current research interest in organic chemistry including, but not limited to alkanes, alkenes, alkynes, alcohols, ethers, alkyl halides, aromatic compounds, carboxylic acids, amides, esters, amines, phenols, amino acids, peptides, proteins, carbohydrates, nucleic acids, heterocycles, organometallics, spectroscopy, secondary bimolecules, polymers, nanochemistry, medicinal chemistry, fullerenes, stereochemistry and organic synthesis.
|SCH521||Advanced Chemical Thermodynamics||45||View Description|
Advanced Chemical Thermodynamics Description
Real gases: Equation of state and reduced equations, Hm, Cp and Sm for a real gas; Solutions, fugacity of solutions, activity and standard states; Dilute solutions and activity coefficients; Deby-Huckel theory and the derivation of activity coefficients; Phase equilibria: Two, three and more phases in equilibria; Multicomponent systems using Gibbs-Duhem equation; Experimental methods; Different types of calorimetry.
|SCH515||Introduction To Medicinal Chemistry||45||View Description|
Introduction To Medicinal Chemistry Description
Historical perspective, classification of drugs, drug targets; Protein structure; Interaction of drugs with biological targets (enzymes, receptors and nucleic acids); Drug development- screening, isolation and purification; Drug transport to site of action, metabolism and excretion; Drug dose levels; Drug design- substituent variation, modification, pro-drugs, clinical trials, structure activity relationship studies, synthetic analogues, lead compounds; QSAR; Anti-bacterial agents: Sulfonamides, penicillins, cephalosporins, tetracyclines; Drug resistance.
|SCH514||Secondary Metabolites||45||View Description|
Secondary Metabolites Description
The occurrence and major biosynthetic pathways for organic compounds (secondary metabolites) isolated from plants and animals: Distinction between primary and secondary metabolites; The acetate pathway- Fatty acids and other polyketides, prostaglandins, thromboxanes, leukotrienes, polyphenols; Phenolic oxidative coupling; The mevalonate pathway: Mevalonic acid, isoprenoids, terpenes (mono-, sesqui- etc), steroids, carotenoids; The shikimate pathway: Shikimic acid, aromatic amino acids, coumarins, cinnamic acid, lignans, flavonoids, alkaloids; Nucleic acids; Product development examples for compounds from different biosynthetic routes.
|SCH513||Advanced Organic Spectroscopy||45||View Description|
Advanced Organic Spectroscopy Description
Chemical shift in 1H-NMR; Factors affecting chemical shift, spin-spin coupling in 1HNMR; Factors affecting coupling constant; Chemical shifts in 13CNMR; Broadband proton decoupling in 13C-NMR; Off-resonance proton decoupling; distortionless enhancement by polarisation transfer (DEPT); Nuclear overhauser enhancement (NOE) in 1H- and 13C-NMR; Pulse fourer transform NMR; Free induction decay; homonuclear correlation spectroscopy (IH, 1H-COSY); Nuclear overhauser and exchange spectroscopy (NOESY); Heteronuclear correlation spectroscopy; Mass spectroscopy: Chemical ionization, fast atom bombardment as applied to organic chemistry and other ionisation techniques. Practicals
|SCH512||Physical Organic Chemistry||45||View Description|
Physical Organic Chemistry Description
General survey of theoretical concepts in organic Chemistry (Physical organic approach); Structure and reactivity; Reaction rates; The transition state; Substituent and solvent effects on reaction rates and mechanisms; Woodward-Hofman rules; Theory of electrocyclic and cycloaddition reactions; Conformational analysis; Cyclic and acyclic systems; Stereochemistry.
|SCH511||Advanced Organic Synthesis||45||View Description|
Advanced Organic Synthesis Description
Survey of synthetic methods: Cycloaddition and related reactions, Diels-Alder reactions, photochemical cycloaddition, allowed and non-allowed reactions; Alkylation: Claisen- Schmidt, Mannich, Michael and related condensations; Sulphur and phosphorus ylides: The Wittig reaction; Reduction and oxidation reactions; Group protective reagents; Introduction to concepts of Green Chemistry and synthetic design.
|SCH508||Chemical Applications Of Group Theory||45||View Description|
Chemical Applications Of Group Theory Description
Principles, definitions and theorems of group theory; Molecular symmetry representations of groups; Group theory and quantum mechanics; Applications; Symmetry aspects of molecular orbital theory, ligand field theory; VIS and UV spectra of transition metal complexes; Metal -ligand bonding; molecular vibrations and symmetry rules.
|SCH502||Physical Methods In Inorganic Chemistry||45||View Description|
Physical Methods In Inorganic Chemistry Description
Development of the theory of spectroscopy as applied to ultra violet-visible, infrared and rotational spectroscopy; Rate of transition and comparison with experimental quantities; Integrated absorption coefficient of known molecules and oscillator strength; Derivation of Boltzmann distribution and its application to atomic absorption spectroscopy; Mossbauer effect theory and chemical shifts in X-ray photoelectron spectroscopy and Auger electron spectroscopy; Inorganic NMR, Electronic Spectroscopy; X-ray absorption, X-ray crystallography; Atomic absorption spectroscopy (AAS); Mass spectroscopy and electrochemistry; Electron spin resonance and inductive coupled plasma-mass spectrophotometer.
|SCH501||Advanced Organometallicl Chemistry||45||View Description|
Advanced Organometallicl Chemistry Description
Review of crystal field theory; Ligand field theory and molecular orbital theory;Structure, bonding and properties of organometallic compounds with б-donor, p- donor and p-acceptor ligands; Structural elucidation methods; Types of organometallic reactions; ligand substitution; Oxidative addition/reductive elimination; Migratory insertion; Attack of coordinated ligand and the reactivity of metallocycles; Carbenes and carbines; Homogeneous and heterogeneous catalysis; Metal clusters; Applications of organometallic compounds. Practicals
|DMS502||Research Methods||45||View Description|
Research Methods Description
Overview of business research; Role of business research; the research process; Quantitative and qualitative research techniques; Critical approaches: Text and discourse analysis; Problem definition and research proposal; Research designs and samples; Data collection, measurement and scaling; Data analysis; Communicating research results; Ethical issues in business research
|SCH522||Advanced Electrochemistry||45||View Description|
Advanced Electrochemistry Description
Electrified interface; The basis of electrodics; The double-layer; the dipole potential difference; The special position of mercury in double-layer studies; The competition between water and organic molecules at electrified interfaces; The Butler-Volmer equation; Equilibrium exchange current density and the non-equilibrium current density; Over potential in non-polarizable and polarizable interfaces; Mechanism of charge transfer: Limiting current density and its practical importance; Polarography and the Ilkovic equation; Hydrogen evolution and electronation of oxygen and their effect on corrosion and the stability of metals.
|SCA503||Advanced Electroanalytical Chemistry||45||View Description|
Advanced Electroanalytical Chemistry Description
Structure of electrode interface, diffusion, kinetic, and thermodynamic factors controlling the rate of reactions at electrodes; Linear and cyclic voltammetry; polarography; Potentiometry; Potential step methods: Differential- and square-wave voltammetry, Amperometric stripping, hydrodynamic voltammetry, rotating electrode technique and electrochemical impedance spectroscopy.
|Level : 2|
|Semester: Non Specified|
|Course Code||Course Name||Course Hours|
A candidate identifies a research topic and develops a concept paper; the student is allocated at least two supervisors from among the academic members of staff to assist the student develop a research proposal; the student presents the proposal at a departmental seminar where the audience critiques the research proposal and makes appropriate recommendations for changes to improve it; the student submits the proposal to the Board of Postgraduate Studies through the Dean of School, for approval; the student conducts the research according to the proposal and under the supervision of the supervisors; the student analyses and presents the results at a departmental seminar for critique and review; the student finalizes the research in a form of thesis for examination.